Language recovery after a perinatal stroke

28 December, 2020

Antoni Rodriguez-Fornells, principal researcher of project “244/14 - Induced brain plasticity after perinatal stroke: structural and functional connectivity”, supported by the BIAL Foundation, published the paper Signatures of brain plasticity supporting language recovery after perinatal arterial ischemic stroke in the journal Brain & Language.

“Brain imaging methods such as functional Magnetic Resonance Imaging (fMRI) and Diffusion Tensor Imaging (DTI) have already been used to decipher the functional and structural brain changes occurring during normal language development. However, little is known about the differentiation of the language network after an early lesion. While in adults, stroke over the left hemisphere generally induces post-stroke aphasia, it is not always the case when a stroke occurs in the perinatal period, thus revealing a remarkable plastic power of the language network during early development. In particular, the role of perilesional tissues, as opposed to undamaged brain areas in the functional recovery of language functions after an early insult, remains unclear. In this review article, we provide an overview of the extant literature using functional and structural neuroimaging data revealing the signatures of brain plasticity underlying near-normal language development”.